Short stature of women live longer

The pursuit of modern people are tall, the pursuit of Gugan Mei, our body with the nutrition changes in the structure generally a lot higher than their predecessors, but our life expectancy has not increased, and along with environmental change, disease, more and more younger . Pursuit of beauty is every woman's nature, but longevity is the ultimate desire of every woman. Scientific research shows that: short stature, petite women more likely to live longer, why?

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According to foreign media reports, according to a new study found that genetic change can make people live longer (which can live to 90 years old or more), and short stature are more women live longer. Yeshiva University Albert Einstein College of Medicine researchers found that genetic variation is an important cell signaling control channel, can influence people's life.



The Einstein College of Medicine researchers report in the United States continued to investigate through the gene encoding the human life span of the latest conclusions drawn so far have been 450 in age from 95-110 years old Ashkenazi Jews involved in the investigation. Because it is from a small group of inherited them than other groups of people in a more simple genetic genetics. Therefore easier to detect gene expression changes and the relationship between the body. In 2003, the "life gene" has been confirmed by previous research projects.



The current study focused on insulin-like growth factor gene in the role, this factor is regulated by human growth hormone, the body of each cell type. Insulin growth factor on the child's growth and provide for their adult tissue synthesis plays a key role. When the molecules in the blood plasma propagation of nerve endings on the cell wall, insulin growth factor cell signaling channel will be triggered. For example, this cell division, it will signal sent to the nucleus.



Animal studies have shown that insulin-like growth factor gene mutation into the channel will lead to two results: may impair the growth of these animals but can extend their life. So Einstein College of Medicine scientists have inferred that changes in the channel signals may also affect life expectancy. They analyzed 384 Ashkenazi Jewish centenarians and insulin-like growth factor-related genetic changes. Because plasma levels of insulin-like growth factor does not reflect the level of their young time, researchers who find the other two groups: a group of children of these centenarians, a group of other children of these centenarians peers, but the family History does not long-lived people.



Obviously, the daughters of centenarians in the plasma levels of insulin-like growth factor to be higher than 35% of girls. This conjecture was proved before the study: the daughters of centenarians is lower than 2.5 cm in the other group. When the researchers analyzed the cell wall of insulin growth factor gene encoding peripheral nerve elements, the centenarian and her daughter, their genes produce more than the other group members variation.



"Our study shows that insulin-like growth factor signaling as a block, these gene mutations on the human life cycle will extend the work, as do animal experiments as before," the study authors, the Association of Einstein Aging Study people 尼尔巴斯莱 said. He pointed out that the drugs reduce insulin growth factor is being used for cancer treatment, and may have anti-aging effect.